Prof. Dr. rer. nat. Edgar Brunner, (em.)
Foto Prof. Dr. rer. nat. Edgar Brunner, (em.)


Institut für Mathematische Stochastik


Goldschmidtstrasse 7
37077 Göttingen

Phone:+49 551 39 4992
Fax:+49 551 39 4995
Mail:brunner@ams.med.uni-goettingen.de
Research interests
* Nonparametric Statistics
o asymptotic distribution of rank statistics
o multi-factor designs
o adjustment for covariates
o rank methods for clustered data
o applications to diagnostic trials
* longitudinal data
* ordered categorial data
* multi center clinical trials
* statistical methods for the analysis of microarray data
* diagnostic trials
Publications
Methodische Originalarbeiten (ab 2000)

1. Munzel, U. and Brunner, E. (2000). Nonparametric methods in multivariate factorial designs. Journal of Statistical Planning and Inference 88, 117-132.

2. Brunner, E. and Munzel, U. (2000). The nonparametric Behrens-Fisher-Problem: Asymptotic theory and a small sample approximation. Biometrical Journal 42,17-25.

3. Munzel, U. and Brunner, E. (2000). Nonparametric Tests in the Unbalanced Multivariate One-Way Design. Biometrical Journal 42, 837-854.

4. Brunner, E. and Langer, F. (2000). Nonparametric Analysis of Ordered Categorical Data in Designs with Longitudinal Observations and Small Sample Sizes. Biometrical Journal 42, 663-675.

5. Brunner, E., Munzel, U. and Puri, M.L. (2001). The multivariate nonparametric Behrens-Fisher-Problem. Journal of Statistical Planning and Inference 108, 37-53

6. Brunner, E., Domhof, S. and Puri, M. L. (2002). Weighted rank statistics in factorial designs with fixed effects. Statistica Neerlandica 56, p. 179-194.

7. Brunner, E. and Puri, M. L. (2002). A class of rank-score tests in factorial designs. Journal of Statistical Planning and Inference 103, 331-360.

8. Domhof, S., Brunner, E. and Osgood, W. (2002). Rank Procedures for Repeated Measures with Missing Values. Sociological Methods and Research 30, 367-393.

9. Munzel, U. and Brunner, E. (2002). An Exact Paired Rank Test. Biometrical Journal 44, 1-10.

10. Domhof, S. and Brunner, E. (2002). Discussion on “A Nonparametric Approach to Matched Pairs With Missing Data”. Sociological Methods and Research 30, 455- 457.

11. Akritas, M. G. und Brunner, E. (2003). Nonparametric Models for ANOVA and ANCOVA: A Review. In “Recent Advances and Trends in Nonparametric Statistics” (Eds. M.G. Akritas and D.N. Politis), 79-91.

12. Bathke, A. and Brunner, E. (2003). A Nonparametric Alternative to Analysis of Covariance. In “Recent Advances and Trends in Nonparametric Statistics” (Eds. M.G. Akritas and D.N. Politis), 109-120.

13. Landgrebe, J., Bretz, F. and Brunner, E. (2004). Efficient Two-Sample Designs for Microarray Experiments with Biological Replications. In Silico Biol. 4, 0038.

14. Kaufmann, J., Werner, C. and Brunner, E. (2005). Nonparametric Methods for Diagnostic Test Performance. Statistical Methods in Medical Research 14, 1-18.

15. Repsilber, D., U. Mansmann, E. Brunner, and A. Ziegler (2005). Editorial: - Tutorial on Microarray Gene Expression Experiments. Meth. of Inf. in Medicine 44, 392 – 400.

16. Bretz, F., Landgrebe, J. and Brunner, E. (2005). Multiplicity Issues in Microarray Experiments. Meth. of Inf. in Medicine 44, 431 – 439.

17. Bretz, F., Landgrebe, J., and Brunner, E. (2005). Design and Analysis of Two-Color Microarray Experiments Using Linear Models. Meth. of Inf. in Medicine 44, 423 – 430.

18. Bretz, F., Landgrebe, J., and Brunner, E. (2006). Efficient Design and Analysis of Two Color Factorial Microarray Experiments. Computational Statistics and Data Analysis 50, 499 - 517.

19. Thangavelu, K. and Brunner, E. (2006). Wilcoxon Mann-Whitney Test for Stratified Samples and Efron's Paradox Dice. Journal of Statistical Planning and Inference (in press).

20. Neubert, K. and Brunner, E. (2006). A Studentized Permutation Test for the Nonparametric Behrens-Fisher Problem. Computational Statistics and Data Analysis (in press).

21. Werner, C. and Brunner, E. (2006). Rank methods for the analysis of clustered data in diagnostic trials. Computational Statistics and Data Analysis (in press).

22. Chen, T.-W., Lin, B.-J., Brunner, E. and Schild, D. (2006). In Situ Background Estimation in Quantitative Fluorescence Imaging. Biophysical Journal 90, 2534 –2547.


Eingeladene Originalarbeiten und Reviews (ab 2000)

1. Brunner, E. and Puri, M.L. (2001). Nonparametric Methods in Factorial Designs. Statistical Papers 42, 1-52.

2. Brunner, E. and Puri, M.L. (2001). Point and Interval Estimators for Nonparametric Treatment Effects in Design with Repeated Measures. In: Data Analysis from Statistical Foundations: Festschrift in Honor of Donald A.S. Fraser, A.K.Md. Saleh (ed.), Nova Science Publishers, New York, 167--178.

3. Brunner, E. (2001). Asymptotic and Approximate Analysis of Repeated Measures Designs under Heteroscedasticity. In: Mathematical Statistics with Applications to Biometry: Festschrift in Honor of Prof. Dr. Siegfried Schach, J. Kunert and G. Trenkler (Eds.). Josef Eul Verlag, Köln.

4. Akritas, M. G. und Brunner, E. (2003). Nonparametric Models for ANOVA and ANCOVA: A Review. In “Recent Advances and Trends in Nonparametric Statistics” (Eds. M.G. Akritas and D.N. Politis),

5. Brunner, E. (2004). Review of the book “Applied Nonparametric Statistical Methods” by P. Sprent and N.C. Smeeton, Statistics in Medicine 23, p. 1988-1989.



Bücher / Monographien (ab 1999)

1. Brunner, E. und Langer, F. (1999). Nichtparametrische Analyse longitudinaler Daten. Oldenbourg, München.

2. Brunner, E., Domhof S. and Langer, F. (2002). Nonparametric Analysis of Longitudinal Data in Factorial Designs. Wiley, New York.

3. Brunner, E. und Munzel, U. (2002). Nichtparametrische Datenanalyse. Springer, Heidelberg.
Courses
Sommersemester 2018
Wintersemester 2017/18
Curriculum vitae
1943 Year of birth
1971 Diploma in Mathematics, RWTH Aachen
1973 Habilitation, RWTH Aachen
since 1976 Professor of Medical Statistics and Head of the Department Medical Statistics
at the Georg-August-University Göttingen

Visiting Professor:
1994, 1996, 1997 Penn State University, State College, USA
1994, 1997, 1999, 2000 Indiana University, Bloomington, USA

Academic Services:
Editor Biometrical Journal
Associate Editor Journal of Statistical Planning and Inference