Modern Aspects of Human Genetics

Lecturer:

Dr. rer. nat. Gökhan Yigit, Dr. rer. nat. Arne Zibat

Course typ:

Seminar

Description:

Human genetics is a dynamic scientific field aiming to identify and characterize the genetic causes of hereditary diseases. Using a broad spectrum of next-generation sequencing-based high-throughput analyses (e.g. whole-genome and whole-exome sequencing, RNA-Seq, Chip-Seq), state-of-the-art molecular biology methods and different cellular systems and model organisms (e.g. mouse, zebrafish) human geneticist focus on the identification of the genetic cause of rare congenital diseases and as well as mutations contributing to our risk of developing certain types of cancer. The deep functional characterization of these gene products, including the molecular pathways in which they are involved, provides us with the opportunity to understand how they act in fundamental cellular processes and how certain mutation give arise to specific human phenotypes. Furthermore, the characterization of these cellular processes and pathways expand our knowledge about the pathogenesis of these rare disorders and, at the same time, enables us to develop new therapeutic strategies including CRISPR/Cas- and iPSCs-based (genome editing) approaches.

In this seminar, we will discuss the current and newest findings in the field of human genetics including novel technological approaches, the latest insides into the molecular mechanisms underlying congenital diseases and state-of-the art therapeutic strategies and consequences.

Please note:
Registration via StudIP is mandatory. You can register for the event between October 14 and October 28, 2025, at 6:00 p.m.
Participation in the preliminary meeting is mandatory – date of the preliminary meeting: Thursday, October 30, 2025, 6:00–6:45 p.m.

Contact person:
Dr. rer. nat. Gökhan Yigit (goekhan.yigit@med.uni-goettingen.de)

Place:

((MED 31 (R. 230, 2. OG), Heinrich-Düker-Weg 12))): Wed.. 18:00 - 18:45 (9x), (MED 31 (R. 230, 2. OG), Heinrich-Düker-Weg 12)): Wed.. 18:00 - 18:45 (3x), (Preliminary meeting - mandatory attendance; MED 31 (R. 230, 2. OG), Heinrich-Düker-Weg 12)): Wednesday, 29.10.2025 18:00 - 18:45

Semester:

WiSe 2025/26

Times:

Wed.. 18:00 - 18:45 (weekly), Dates on Wednesday, 29.10.2025 18:00 - 18:45
Preliminary discussion: Wednesday, 29.10.2025 18:00 - 18:45
First appointment: Wednesday, 29.10.2025 18:00 - 18:45, Room: (Preliminary meeting - mandatory attendance; MED 31 (R. 230, 2. OG), Heinrich-Düker-Weg 12))

Course number:

440850

Participants:

MEDK ab 5 M.Bio 1 - 4 Mol Med - BSc: > 3. study semester; MSc: > 1. study semester Bio 1 - 4Cardiovascular Sci MSc

Pre-requisites:

for MolMed-Students: Successful participation of Module B.MM.106 (Molekulare Zellbiologie und Molekulare Genetik) or equivalent course Recommended previous knowledge: Basic knowledge in molecular genetics, cell biology and human genetics

Area classification:

Vorlesungsverzeichnis SoSe 2024
Vorlesungsverzeichnis WiSe 2025/26

Further information from Stud.IP about this course

Home institute: Abteilung Humangenetik
Participants registered in Stud.IP: 12
Number of postings in Stud.IP forum: 2
Number of documents in the Stud.IP download area: 13